Corneal subepithelial monoclonal kappa IgG deposits in essential cryoglobulinaemia.

نویسندگان

  • I Kremer
  • P Wright
  • S Merin
  • J Weiss
  • A I Pick
  • H Kaufman
چکیده

A 60-year-old man suffering from photophobia and visual disturbances was found to have bilateral superficial corneal grey-white gelatinous deposits. An abnormal cold-precipitable serum component was found and characterised as homogeneous IgG-kappa immunoglobulin. Corneal immunohistochemical examination revealed subepithelial IgG-kappa deposits, focally replacing Bowman's layer. The patient underwent superficial keratectomy in both eyes with satisfactory visual results.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

[Crystalline keratopathy due to kappa chains in a monoclonal gammopathy].

CASE REPORT The following case shows corneal crystal formation in a patient in whom thee systemic work-up led to the diagnosis of a monoclonal gammopathy with increased monoclonal immunoglobulin G (IgG). We present the corneal signs and subsequent haematological investigations undertaken to establish this important association. DISCUSSION Systemic work-up of a patient with corneal deposits sh...

متن کامل

Delayed onset of membranoproliferative glomerulonephritis in a patient with type I cryoglobulinaemia.

Key words: IgG cryoglobulinaemia; leukocytoclastic festations in their study of 21 patients with type I cryoglobulinaemia in 25% of cases. The renal mani-vasculitis; monoclonal cryoglobulinaemia; membrano-proliferative glomerulonephritis (MPGN) festations may result from massive subendothelial deposits of cryoglobulins, or diffuse glomerulonephritis with subendothelial deposits similar to those...

متن کامل

Fibrillary comma-shaped electron-dense organized glomerular deposits associated with cryoglobulinaemia

A 51-year-old caucasian lady was hospitalized because of purpuric papules of the lower extremities, myalgias, arthralgias, haematuria and proteinuria. Her blood pressure and renal function were normal. She had a history of cerebrovascular accidents, and a previous nuclear magnetic resonance showed three ischaemic lesions. Laboratory work-up including liver function, hepatitis B surface antigen,...

متن کامل

Non-Randall proliferative glomerulonephritis with humps and monotypic IgG deposits in primary Sjögren’s syndrome: a first case report

Renal involvement is frequent in patients suffering from primary Sjögren's syndrome (pSS). Tubulointerstitial infiltration is the most common renal lesion, while glomerular involvement is rare. We report the case of a 50-year-old woman with pSS who developed renal failure due to an unusual proliferative glomerulonephritis with humps and monotypic IgG1-kappa deposits. Searches for cryoglobulinae...

متن کامل

Corneal electrolysis for recurrence of corneal stromal dystrophy after keratoplasty.

AIMS To evaluate corneal electrolysis as a treatment for recurrent diffuse corneal opacities at the host-graft interface of the stroma or at the subepithelial region in two types of granular corneal dystrophy (GCD). METHODS Recurrence developed at the host-graft interface of the stroma after lamellar keratoplasty in a patient with Avellino corneal dystrophy (ACD). At surgery, the deep aspect ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The British journal of ophthalmology

دوره 73 8  شماره 

صفحات  -

تاریخ انتشار 1989